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Genetic Obesity Mutation Shows Unexpected Heart Health Benefits, Reviving ‘Thrifty Gene’ Theory

A groundbreaking study reveals that genetic mutations causing severe childhood obesity may also provide protection against cardiovascular disease. The findings challenge conventional views of genetic “defects” and could lead to new treatments for heart conditions.

Unexpected Dual Effects of Obesity Gene

Researchers have discovered that a genetic mutation strongly linked to severe obesity may paradoxically protect against heart disease and high cholesterol, according to a new study published in Nature Medicine. The findings potentially revive the long-debated “thrifty gene” hypothesis and could open new pathways for cardiovascular treatments.