Unlocking Nature’s Gene Editors: How Retron Systems Are Revolutionizing Genome Engineering
The Hidden World of Bacterial Retrons In a groundbreaking study published in Nature Biotechnology, researchers have uncovered a treasure trove…
Tag: HEK 293 cells
Researchers Engineer Custom Calcium Channels Through Computational Protein Design
A breakthrough in protein design enables creation of custom calcium channels from scratch. The approach uses generative AI to build channels around precisely defined selectivity filters, achieving calcium selectivity that eluded previous methods.
Breakthrough in Custom Ion Channel Engineering
Researchers have reportedly developed a novel computational approach to design custom calcium-selective ion channels from scratch, according to a recent Nature publication. The method represents a significant advancement in de novo protein design, enabling scientists to construct ion channels with precisely specified selectivity filters that determine which ions can pass through.
Engineering GPCR Signaling Precision Through Allosteric Modulators
Revolutionizing GPCR Therapeutics with Targeted Allosteric Modulation G protein-coupled receptors (GPCRs) represent one of the most important drug targets in…